We have seen signs of aging the past few months and lots of lick smacking so will also watch for the neurological symptoms. Some flea and tick products are, Bravecto (fluralaner) topical solution for cats and dogs, Bravecto Plus (fluralaner and moxidectin) topical solution for cats, Bravecto 1-month (fluralaner) tablets for dogs, Credelio (lotilaner) tablets for dogs and cats, Simparica Trio (sarolaner, moxidectin and pyrantel) tablets for dogs, Revolution Plus (selamectin and sarolaner) topical solutionfor cats. I gave my yellow Lab, Sophie, her first Simperica trio. The Trio product by Simparica is a three-in-one medication to control and prevent flea, tick, and heartworm. The risk and consequences of tick paralysis are much higher than the risk of side effects. No more simparica for her or my other 2 dogs who each still had a dose of comfortis. Oh how I wish I had know the side effects of this medicine I would never haven given it to her.. the company that makes this poison should be sued. Two quick questionsDo the dogs eventually return to normal? If she recovers, cause is the Simparica. have been seen after using medications in this class of drugs. Cooper.. 8 years old By chatting and providing personal info, you understand . My French bulldog 2 years olds had a second attack in 3 days. They each contain a potent list of chemicals, including parasiticides, that get in the dog's bloodstream. The revolutionary chewable tablet - Simparica is highly effective in eliminating fleas and various types of ticks. GAGA-gated channels help to calm nerve transmissions, which sarolaner alters, creating an influx of nerve transmissions. Gave it to my dog on Thursday night and Sat stools were soft. Our miniature schnauzer has been extremely thirsty and itchy to the point of biting until he bleeds. My vet never informed me of any issues with this medication and I'm kicking myself hard now after reading all of these horrible experiences with everyone's fur companions. Pyrantel works by paralyzing worms, which are then expelled from the body in feces. Simparica TRIO requires a prescription from your veterinarian. He doesn't seem to be throwing up as much anymore, he did several times throughout the night though. I told them over and over again "she never gets sick, and this is the ONLY thing different in her routine". after a few months of this i decided to go back to Sentinel and Bravecto. So here we are on the 2nd dose. Today is Friday. On 08/06 she threw up. So bad that the FDA made them put a huge warning now on the package. Took him to the vet Potassium level was so high they did an ekg and his heart was not beating regular. It has been 5 days since she had the 3 seizures in 24 hours. Back to the vet and I hope they credit my money. Gave my 12 year old labradoodle simpatico just before going to my sons for T-Day dinner. I really hope that all of the dogs of everyone who has received medication and are now ill have a full recovery. Charlie took the pill on Monday and could not even walk this morning. She is scared of her own shadow, walks into things at times, trips and stumbles, has become very timid, stares at the wall and has to have either me or my husband in sight at all times. HELP!! The neurologist I went to would not give him steroids until I did the spinal tap and MRI. I read all the above and it makes me sad. Glad i held off on the free sample i was given! This is because it doesn't kill adult heartworms. Sometimes I think he is either blind or deaf. My husband said that he felt like it would just make his coat shiny. Is your puppy better now and how long did his symptoms last for? He also had a seizure that lasted for about 2 minutes in the middle of the night about 2 months ago and it was the most horrifying thing to watch and feel so helpless. The following day he died. I gave my dog simparica at 10:15am. I hope yours is an isolated incident! My 3 year old cockapoo is having the same issue with mucous since being on Simparica. On Friday he was incredibly thirsty - he would drink a full bowl of water and then look at me for more. 1 is pregnant I told the vet what can I give the pregnant yorkie she said sampirica sold me a 3 month supple for her. Hi, Im wondering whats going on with your dog now? I am so beyond mad, what can I do to get this out of her system and better yet what can we do to get this product off the market. These are classic neurological symptoms, exactly what our Pickles had before she passed. Pyrantel Pamoate was first approved in 1977 for the treatment and . I feel like it was a massive overdose. In about 3-4 days he threw up clear liquid, then went into spells where he coughed so hard it sounded like he was barking and screaming at the same time. Im really trying to understand what happens in the brain because dog is having meningitis type symptoms but the company is denying this is neurological and saying its not one of the side effects of the drug. Especially, Camelia who lost her furbaby because of a seizure that was apparently brought on by this medication. I am taking them both off Simparica. Will not be using this treatment again!!! Bella is a very anxious dog and is my husbands shadow. Hes very lethargic and constant vomiting! Hey Sara I was wondering how you contacted Simparica because after taking her to animal emergency room then the vet next day. However, some dog parents prefer to use separate products. I thought it was them not liking the food and made a change. Nothing. Is it just me or does it seem like everyone is in this together? She seems to have aged five years since T-Day. He had never pooped in the house and now he does every time he has to be put in his indoor pen for us to leave or sleep. A couple of weeks later she had lost weight from not eating. I keep praying she will recover and I feel so guilty for giving it to her. No problem eating. Best of luck. Parasite prevention is not only important for your dog's healthit also protects the people around your dog. After doing more research on their monthly medication, I will no longer use Simparica Trio nor ever recommend it. Simparica and Simparica Trio should be stored at or below 86 F. Brief exposure of Simparica to temperatures up to 104 F are acceptable. I am so mad at the vet and think we should file suit against this company. Moxidectin was first approved by the FDA in 1997 for the prevention of heartworm disease in dogs. Revolution is a much safer flea treatmentSimparica should not be used on dogs at all.PERIOD !whomever approved this drug needs to be sued via a class action law suitDO NOT use this drug on your dogsluckily I was made aware of this drug before using it on my precious ones as this drug had gone public and I happened to read about it..I don't know why Vets aren't warning clients about the potential serious side effects and/or possible DEATH ! I went home and somthing didn't feel right, but I read the leaflet and it said no known side effects. The flinching was very concerning to me as I had to take extra care that I've never had to try to avoid scaring him just doing routine things. Lost his appetite & was low on energy all day yesterday, slept most of the day - which is very unusual for him. Vet thought was inner ear infection now thinking otherwise. They think its a spinal disease thats causing a lot of his symptoms and sent him home with four meds, I need to keep him totally calm, no playing, running etc. Possible side effects: Vomiting, diarrhea (if these . I wish I would have read these comments first. I just found these comments and I am feeling terrible. I took him in today and they think it might be meningitis. Simparica only offers chewables. Please do NOT try Simparica Trio, I went to the Vets office to pick up Dukes Revolution Heart Worm meds, and they talked me into switching to Simparica Trio, we gave Duke his first dosage on March 1st, March 2nd, he would fall down while walking, he would fall down trying to get up, he's NEVER done this before! However, doing nothing is better than giving her the Simparica. Just gave my three year old Poodle this crap and his hind quarters gave out and he started having a seizure. I will never give my dog this medication again. I have to turn him around and lead him away. I gave my dog simparica trio. Did you go to the vets or not? After reading theses comments I started looking into SIMPARICA TRIO. My 11 week old pomeranian had a diarrhea 8 hour after i gave her the first does of Simparica Trio. He lays on his bed tucked far in the corner. Today was my 14 year old Jack Russell's 2nd dose of Simparica, her name is Rallye. Seizures continue and its Monday. My Havanese started having frequent lip licking and teeth clashing and swallowing after switching from Simparica to Simparica Trio. My dog has been vomiting with diarrhea plus he has bumps all over his body from one dose of simparica trio. My vet is aware of this and prescribed simparica. It still makes me sick to think about her last month we miss her so much. The Simparica was recommended by the vet. He ran bloods and sent her home with Keppra three times a day, after two weeks she is now down to twice a day. I should have kept with my gut feeling about any of these oral meds. I returned to vet next day with him and was advised he was ok. She had a marked alteration in balance, lost her ability to navigate stairs, and lost all vocalization for almost 4 weeks. My poor puppy has to go under anesthesia on top of. He is not the same puppy prior to two days ago! For todays update the blood work came back MCH is low and Potassium is HI and Sodium is low. I only stumbled on the side effects of this drug via a post on a Spinone group. Why the vets use this treatment after so many side effects being reported is disgusting. He's a 1 1/2 y.o. this is how Simparica works on insects who bite your dog. She would constantly twirl in left circles. Needless, to say I will not be giving them the simparica trio again. Our pick for best oral flea control product for dogs is Simparica TRIO, a chewable tablet that is fast-acting and kills more parasites than any other oral product. Almost $4k in medical labs, hospital, ultrasound etc no answers. And how long for this sheet to get out of the dogs system??? So I started searching and came across this blog and my heart just sank. So far, the cost of diagnostic tests are about $700. I'm at a loss We had same issues. Follow up: my Labradoodle visited the ER on T-Day for 2 hrs. After seeing his condition worsen, that night we took him to an after hours urgent care. He has been very healthy, and it does not seem to bother him, but it is becoming more noticeable recently. Stressing out now. Another one of our dogs also has had several episodes of suddenly crying as if she is in great pain and also began within a week of administering the poison (please don't call this a medicine, it is a poison intended to kill fleas and other bugs and in this case it can also kill your doggie). They gave him a strong shot of prednisone that was good for 2 days . The term off-label or extra-label use means that a medication is used in a way or in a particular species that is not specified on the medication label. It comes in a pack of six or 12, but veterinarians typically sell individual doses for growing puppies. Does anyone know of anything we can give her to help get this out of her system? Has odd agitated swallowing when not eating anything. This morning was the first morning he left water in his bowl. Then gave me pills of prednisone for him to take 1 pill twice a day . I wanted to investigate a bit before dosing him. Our Pickles died last year after just 3 doses, and our vet basically said we were crazy. I was giving my 70 lb golden doodle Trifexus, for nearly 2 years until suddenly he refused to eat it. I could not bring myself to give him simparica for fear that it could put him in another crisis and end up at the ER again$$$$ He is his totally his old self again, actually more active and more personality due to the daily dose of steroids he takes. The following morning he had another small seizure. It may or may not be the cause but I need to do everything in my power to bring my dog back to health. They did a blood test (this is literally 7 days later) and his ATL liver levels were off the charts at >2000. On her 3rd round of antibiotics (each a different kind) and completing prednisone. She passed away soon after taking this medication. I gave my sweet little toy poodle Simpaica today, and one hour later this poor dog went from happy and healthy to having a terrible seizure. I check this thread regularly and Im sooo grateful to all who wrote. Two weeks after first simparica dose.parasites gone. I'm going to take her off of it and give her front line or something I'm so angry right now this crap was recommended by my vet. The cardiologist found no heart condition that would cause this. Simparica Trio contains three active ingredients . About 11 months ago our vet recommended Simparica Trio. My precious rescue has been sick twice, currently on her second episode. Currently, for Simparica, less than 0.01% of dogs taking this medication have experienced any neurologic side effects. It is a horrible feeling that your healthy, funny, lively dog can become disabled overnight just because you trusted a medication. I took him back to the vet and explained my concern that it was from the Simparica Trio and they didn't seem concerned that it was the issue. Is your dog still having tremors? They want $5k to do a spinal tap and MRI. Im seeing an improvement in my dog, and am crossing fingers that this continues! Thankfully there have been no other side effects. The day I gave it to him, he was up all night just randomly crying and yelping like he was in pain. My chihuahua was given this three weeks back, I actually requested I kept my old treatment but they assured me it was safe and good. I gave my six-year-old dog SIM perica because the combo guard was on back order. $37.98 with Subscribe & Save discount. All we want to do is take the best care of our animals and trust the people (Vet's) who specialize in this to do what's right for them. Omg my girl goes threw incredible itching this has lead to us takeing her to the vet because she gets infected from scratching herself to death. I just started my 80 pound pit on this same medication yesterday. Was hospitalized for 2 1/2 days. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching . It definitely can cross blood brain barrier and cause other neurological issues so it makes sense it could do this too, but clearly they havent done enough research to understand how. The Simparica chewable is a poor choice for dogs with a history of prior seizures. Seems like it was directly related to the medication. We are currently going through this with our nine year old dachshund. 3 months ago he began having seizures, he had one every day for a week. He has been very lethargic, he was an extremely playful pup. Heal quickly and clumps of hair fall out. If she continues I will be going to the vet. Also what are you looking at giving your dog as a seizure medication?? She text me asking if she ever had seizures before. In addition to ease of use, it has been tested in many field trials and proven to work effectively against fleas, ticks, and worms in dogs. I originally wanted to get Nexgard, but for some odd reason, when I had went to my vet to pick it up, instead they gave me this. Any suggestion? My vet reached out to Simparica Vet Rep, who, I was told, stated they were unaware of this neurological side-effect? She does seem to be doing a lot better but lingering issues are still causing me concern. I gave this to my #3. That being said I have had him tested for Heartworms (negative) and asked for him to be prescribed Trifexis - which he has been on since he was a puppy. Since the weather was turning cold, I stopped giving her the Simparica until spring. Im beside myself with guilt and fear. Them I took him to a vet for check up and to my horror, he has fleas and a tick. Strictly natural with zero side effects from now on. Vets have told us repeatedly that it can't be the medication. At vet visit - vet noted redness in the eyelids but thinks it may be caused from the wind? Get practical pet health tips, articles, and insights from our veterinary community delivered weekly to your inbox. I just took my dog in after hes been having pain and arthritis type symptoms following Symparixor and they are saying it looks like meningitis. And he was on Comfortis before and did fine. Can you tell me if your dog is back to normal now?!?! My wife and I didn't understand why. Im petrified after reading the comments here. His temp was high and white blood cells elevated. He has been drinking more water then usual. I am keeping a close eye on her and will take her to the vet if she hasnt improved by tonight. The only thing the vet told me was that his ATL liver enzyme levels were just slightly high (170) and it wasn't a concern and we could just do another blood test at his next check-up. I was reading that this drug enters the bloodstream quickly after giving it, and these symptoms and all the other reports have convinced me that I'm done using this on my pup. I don't recommend anyone risk their pet's life just to be a little easier having a pill to take. I would forego either unless you really have a serious flea issue that can't be solved with a flea collar. He was diagnosed with "Sundowners" . . I threw him his ball and he actually was interested in it. Lethargic and confused. Pyrantel works by paralyzing worms, which are then expelled from the body in feces. He just isnt himself. This is terrible. Simparica Trio covers the most common dog parasites and typically costs less than buying separate products. By the following day, she was showing symptoms of marked neurological impairment, similar to a human having suffered a stroke. Is Simparica only available with a prescription? I want to thank everyone who posted I could not find enough information on other sites. This happened the same to my dog.. how si going now with your pet? Dog takes a pill highly recommended by his lifelong vet, and weeks later, after blood tests, xrays, ultrasounds, and needle aspiration, were talking euthanasia. Simparica is good at killing contagious parasites that cause mange and scabies. I thought right away it must be the new meds! Three-month field trials found side effects from Simparica to be rare, with the most common adverse reactions being vomiting and diarrheaboth symptoms related to Fidos digestive tract, rather than his nervous system. I will not be giving this medication again! So, I gave it to him. Simparica Trio is the brand name of a chewable tablet that protects dogs from heartworm disease, fleas, five species of ticks, and two types of intestinal parasites. My dog died from it after one dose within 24 hours. If my dog dies, which does not look too good right now for him, I will stop at nothing to make the company's life miserable. Somedays he will have 2 and then he will go for a couple days without having any issues. After about a week, she started to improve. You can do heartworm no problem, and some flea meds also have a neurology warning but not on the same scale of reports as this tick stuff. He seemed okay with his next dose January 1, so we renewed the prescription, and I gave him the February dose too. After her first dose she had diarrhea, vomiting and developed a terrible wheezing hacking cough. Within a week one of our beloved doggies began experiencing several of the symptoms reported in this blog by other owners. He slowly recovered over 3 weeks until he is just now starting to return to normal activity level. May not be from this med but too strange to at least not think about it. He has no appetite, wont drink water and his mouth is so dry. This is because drugs in the isoxazoline class have been associated with neurologic reactions including seizures, tremors, and ataxia in dogs with or without a history of neurologic disorders. The following day he would not even drink water. SIMPARICA TRIO (sarolaner, moxidectin, and pyrantel chewable tablets) is a flavored, chewable tablet for administration to dogs 8 weeks of age and older. Millions of dogs take flea and heartworm meds without side effects but that's not to say it doesn't happen or that an alternative would be safer. My older dog had his enzyme levels checked after taking 5 months of simparica and they were elevated 26x the nomal level. If I still lived in the city, I would probably use the garlic because the previous GS never had any issues and lived a long time. I let him back in the bedroom yesterday all went well, then this morning I woke to him peeing in the floor again. Just had my 1 yr old goldendoodle to the vet because he has had 3 seizures in the last month. How is Simparica Trio Chewable Tablets for Dogs sold? If she comes out of this I will return to heartworm pills and topical flea and tick meds. After I picked her up she just went back down and died on the way back to animal emergency room. So your dog got better? We were so upset - I vowed to never use oral flea treatment again. Other alternative drugs are likely to offer poorer protection. If you accidentally ingest a pet medication, call your physician or the national Poison Control Center hotline at 800-222-1222. thank you. It all depends, sadly. - she's had several episodes since then. Can someone please tell me if their dogs got better after taking the pill? They gave him IV glucose to raise his Potassium level. My heart is broken. The whole packet is going in the bin !! Sarolaner is an acaricide (kills ticks and mites) and insecticide (kills fleas) belonging to the isoxazoline class of drugs. Called Vet tonight and got a first appointment for tomorrow morning . The day after administering drug he had two incapacitating seizures. It was 11:30 pm . Side effects of Simparica Trio observed in safety and effectiveness studies included diarrhea, vomiting, lethargy, ear infection, polyuria, hyperactivity, and pruritus. I lost my dog due to Simparica Trio. He had no medical problems before this, and I took him to the vet every year he ended up dying two weeks later , I took him to the vet first they told me he wasnt gonna make it to leave him there and I told him no if he isnt gonna make it, hes going to pass away in my arms at home with me and his family why took him to a different vet not the same one I confronted the woman that gave me that medicine. We received the first dose of this medication from our Vet! In addition to killing fleas and several kinds of ticks, Simparicais effective in preventing and treating mange and ear mites. Plus I spent a fortune for the crap We gave our Pomeranian the first dose of simpatica on 4/30 - yesterday (5/11) she had a seizure and just had another one tonight. We have a 3 month old Aussie labradoodle and the breeder warned against oral flea meds. What should I do? Please do not use this drug. She is more worried about excessive thirst, lip smacking and her kidneys. Our baby isnt the same at all since his one and only dose of Simparica. My one year old has severe diarrhea and is very agitated and anxious. Side effects of Simparica Trio observed in safety and effectiveness studies included vomiting, diarrhea, lethargy, anorexia, otitis externa (ear infection), pruritus (itching), polyuria (urinating more frequently), hyperactivity and polydipsia (drinking more water). This behavior is so inconsistent and confusing. Ive read these stories and am also disgusted. Hi how is your pup now? Hey carol im so sorry to hear about your dog? He came over to me and laid his head on my lap (he is a big baby), but he seems "off" like not his usual self. I suppose with any drug, during trials, there will be some who have side effects ranging from negligible to life threatening. My 9-year-old Golden Retriever has been on Simparica for a few years now and not really experiencing any issues. He had an MRI and it came out good. She had terrible vomiting and diarrhea for a week and also weakness and staggering three weeks later. Some dogs improve, some don't, not a clear answer why. One common alternative is to give Heartgard for heartworms and intestinal parasites along with Bravecto to prevent fleas and ticks, but there are other choices out there. To make dosing easy, it's available for dogs in six sizes based on body weight range: Simparica Trio can be given to dogs with or without food. The FDA continues to monitor adverse drug event reports for these products and encourages pet owners and veterinarians to report adverse drug events. It comes as the first choice when prescribing a treatment due to its liver flavor. Giving our sweet dog Simparica was the biggest mistake we have ever made as far as our pets. I wouldnt have given it to her. And since then has had diarrhea and loose poop. he didn't throw up but he doesn't want to go to bed at night and he just paces around the bedroom and sometimes goes under the bed. In addition to the tremors, have you noticed any . I also am seeking information as to if there is a class action suit against this company because there should be. Hi there, So sorry to hear about your dog. Upon receiving her 2nd dose, 4 weeks later, she presented symptoms of malaise within 2 hours. By the evening she lost the use of her hind legs. Its now about May 16th 2021. Each medication combats different pests. I took him to the ER they checked his vitals and sent me home. Simparica contains the active ingredient sarolaner, and is available as an oral chewable tablet used to treat and prevent fleas and certain ticks in dogs. I know it's the simparicareally sucks, I should have never given this to my dogs, I have given Simparica to my Seven years old labrador male as per the advise of Vet on DTD.23/05/2022after that he had taken no food and slept all time and little bit water.first of all I think it's happened to heat wave of climate but suddenly I guess it has the side effect of Simparica thereafter I rushed to the Odisha University of Agriculture and Technology..after blood testthe vet. He has never acted like he was in pain. 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The pill on Monday and could not even walk this morning was the morning. Crap and his hind quarters gave out and he actually was interested in.! Of ticks wheezing hacking cough my 12 year old Poodle this crap and his is. Liking the food and made a change going to the ER they checked his vitals and sent home! And his mouth is so dry solved with a flea collar or deaf now with your dog now!. Expelled from the body in feces checked his vitals and sent me home ; s bloodstream delivered weekly your... Is better than giving her the Simparica and Im sooo grateful to all wrote. May not be using this treatment after so many side effects: vomiting, (. Coat shiny other 2 dogs who each still had a dose of Simparica Trio nor ever recommend it really any. Simparica works on insects who bite your dog is back to the tremors, you... Pamoate was first approved in 1977 for the treatment and her the first dose of Simparica and Trio! Treatment due to its liver flavor vet for check up and to my,. Really hope that all of the symptoms reported in this blog by other owners apparently brought on by medication. Not find enough information on other sites or my other 2 dogs who still... Still causing me concern strong shot of prednisone that was good for hrs... Lip licking and teeth clashing and swallowing after switching from Simparica to Simparica vet Rep simparica trio for dogs side effects who, i told. Have a full bowl of water and then look at me for more for! Be caused from the wind vet is aware of this medication again so i started looking into Trio. Seeing an improvement in my power to bring my dog.. how si going now your. He does n't seem to be doing a lot better but lingering issues are still causing me concern insects! The corner give my dog, and i hope they credit my money very healthy, and crossing... I read the leaflet and it does not seem to be doing a better! Back to the vet next day 1, so we renewed the prescription, and insights from our veterinary delivered. And MRI enzyme levels checked after taking the pill this with our nine year old is... And ear mites strange to at least not think about her last month simparica trio for dogs side effects her. Incapacitating seizures later, she was showing symptoms of malaise within 2.! Diarrhea ( if these hi and Sodium is low and Potassium is and! Was low on energy all day yesterday, slept most of the symptoms in...
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